NA Proactive news snapshot: CytoDyn, Humanigen, Ideanomics,  Alpine 4 Technologies ...

CytoDyn Inc (OTCQB:CYDY) revealed that the US Food and Drug Administration (FDA) provided guidance on adding an open-label extension to its Phase 3 trial (CD12) of its flagship drug Vyrologix (leronlimab) and “specific criteria for the continuation of eINDs for patients” meeting the inclusion and exclusion criteria. The Vancouver, Washington-based late-stage biotechnology company said the CD12 protocol will be amended for adding the open-label arm extension and submitted to the FDA on December 28, 2020. “Upon clearance, each CD12 participating clinical trial site will have the option of enrolling additional qualified patients, with all patients receiving leronlimab,” said the company in a statement. Treatment of qualified patients will continue until the trial’s data is unblinded. Humanigen Inc (NASDAQ:HGEN) announced that the US Patent and Trademark Office has issued a patent to the company for the use of its lead drug candidate lenzilumab in preventing and treating an immune hyper-response called cytokine storm and neurotoxicity in patients undergoing chimeric antigen receptor T (CAR-T) cell therapy. The Burlingame, California-based clinical stage biopharmaceutical company said the patent covers the use of lenzilumab to prevent or treat cytokine release syndrome (CRS), neurotoxicity and otherwise inhibit or reduce incidence or severity of CAR-T-related toxicities in patients undergoing CAR-T cell therapy. Ideanomics (NASDAQ:IDEX) said it's Mobile Energy Global (MEG) unit and contracting entity Qingdao Chengyang Medici have signed an agreement with Meihao Chuxing to purchase an initial 2,000 units of its ride-hailing vehicle model, BYD D1. The vehicle is the world’s first custom-built, all-electric car specifically for ride-hailing with smart technology, safety, and comfort features for both drivers and passengers. The BYD D1 vehicles are intended for deployment in multiple cities within China, with deliveries expected to begin in the first half of 2021. In a separate statement on Thursday, Ideanomics announced that Dr Bruno Wu will step down as the group's executive chairman effective from December 31, 2020, and Alf Poor will succeed as interim-chairman. Alpine 4 Technologies, Ltd., (OTCQB:ALPP) owner of leading small market businesses, announced on Friday that its board of directors has voted to up list to the NASDAQ. In a statement, Kent B. Wilson, Alpine 4 Technologies CEO, commented: "It has become clear to me that this is Alpine 4's moment. We have the opportunity to effectuate a new phase in our public ownership by uplisting to the NASDAQ. The significance of this change will bring important benefits to our current and future shareholders, as well as, our employees. Timing is everything and there is a collective energy propelling Alpine 4 forward and we intend to capture that zeitgeist. It's important that we take advantage of this opportunity quickly so that we can attract the right banking and capital market investors to Alpine 4. These windows of opportunity can be fleeting and hence we are acting resolutely and expeditiously." American Resources Corporation (NASDAQ:AREC) has announced that it will ring the Nasdaq closing bell on December 29, 2020, in celebration of the commencement of operations at its premier mining site, Perry County Resources (PCR) complex and the launch of the company's critical and rare earth mineral subsidiary, American Rare Earth earlier this year.  The company, a next-generation and socially responsible supplier of raw materials to the new infrastructure marketplace noted that the restart at PCR comes after a year of implementing a methodical restructuring and in response to increased demand for raw materials for steel and infrastructure projects and is expected to provide significant revenue growth beginning in 2021. The bell-ringing will take place at 4.00pm EST, signifying the close of the day's trading session. Genprex, Inc. (NASDAQ:GNPX) on Thursday announced the closing of its previously announced registered direct offering of 3,116,884 shares of its common stock with a single healthcare-dedicated institutional investor.  The offering was priced at-the-market under Nasdaq rules at a price of $3.85 per share for gross proceeds to the company of $12 million, before deducting commissions and estimated offering expenses. There were no warrants issued in the offering. A.G.P./Alliance Global Partners acted as sole placement agent for the offering. The company said it intends to use the net proceeds from the offering for working capital and other general corporate purposes. Group Eleven Resources Corp. (CVE:ZNG) (OTCMKTS:GRLVF) (FRA:3GE) on Thursday announced a non-brokered private placement of up to 23,077,000 shares at a price of C$0.065 per share for gross proceeds of up to C$1,500,005. The group said that proceeds from the offering will be used to fund further exploration on its projects in Ireland, including drilling at the company's zinc-lead zone near Carrickittle, as well as for general and administrative purposes.  Fireweed Zinc Ltd (CVE:FWZ) said the TSX Venture Exchange has accepted for expedited filing a mineral property purchase and sale agreement dated November 20, 2020, between Fireweed Zinc and Questex Gold & Copper Ltd., whereby the company will acquire 410 mineral claims, together with all pertinent assets, permits and licences, in the Macmillan Pass area, Yukon, Canada. The property consists of the Bach property, Nid property, Sol property, NC property and Ben property. Under the terms of the agreement, the company will make a $100,000 cash payment and issue 350,000 common shares of the company at a deemed value of 86 cents per share in consideration of the acquisition. The vendor retains a 0.5% net smelter return (NSR) royalty on base metals and silver, and a 2% NSR royalty on gold, as may be derived from the property. GGX Gold Corp. (CVE:GGX) said the TSX Venture Exchange has accepted for filing documentation with respect to its non-brokered private placement announced on November 25, 2020, and December 14, 2020, which will see the issue of 3,052,500 flow-through shares at a purchase price of 16 cents each, together with 3,052,500 share purchase warrants at an exercise price of 20 cents for an 18-month period, subject to an acceleration right, with 26 placees. OTC Markets Group Inc. (OTCQX:OTCM), the operator of financial markets for over 11,000 U.S. and global securities, has announced that Better Choice Company Inc. (OTCQX:BTTR), an animal health and wellness company, has qualified to trade on the OTCQX Best Market and today upgraded from the OTCQB Venture Market. Graduating to the OTCQX Market marks an important milestone for companies, enabling them to demonstrate their qualifications and build visibility among US investors. To qualify for OTCQX, companies must meet high financial standards, follow best practice corporate governance, and demonstrate compliance with applicable securities laws. Michael Young, chairman of Better Choice Company, commented: "Trading our common stock on the OTCQX Best Market will greatly increase the visibility of Better Choice and provide our shareholders the opportunity for greater liquidity in their investment. This is another very important milestone as we continue to broaden our investment base and accelerate our growth strategy. This step provides Better Choice the added monetary flexibility that will help fuel our business development, acquisition ability and overall corporate expansion."